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Identifier 000371892
Title Διαταραχές ύπνου κατά το τρίτο τρίμηνο της κύησης και επιπτώσεις στην έκβαση του τοκετού και την υγεία του νεογνού
Alternative Title Sleep disorders at the third trimester of pregnancy and adverse birth outcomes
Author Μιχελή, Αικατερίνη
Thesis advisor Χατζή, Λήδα
Reviewer Κογεβίνας, Μανόλης
Abstract Background: Sleep disorders are common complaints among pregnant women and may be associated with maternal and fetal complications. The association of sleep disorders in pregnancy with adverse birth outcomes still remains elusive and the exact mechanisms involved are not well established. Objective: The objective of this study, was to examine the association between sleeping habits in the third trimester of pregnancy and adverse birth outcomes including low birth weight, Fetal weight Growth Restriction, and preterm births, in the population-based mother-child cohort study (“Rhea” Study), in Crete, Greece 2007-2009. Methods: We evaluated 1086 women with singleton pregnancies, recruited in the “Rhea” Study, with complete data for sleeping habits and birth outcomes. Participants were asked to complete detailed questionnaires that covered demographic and medical features and sleeping habits. Information on anthropometric measures at birth was obtained from the hospital delivery logs and medical records. Multivariate log-binomial regression models were used to estimate the associate between sleeping habits during pregnancy and the outcomes of interest, adjusting for potential confounders. Results: Women with severe snoring were at high risk for low birth weight (RR 2.58, 95 95%CI 1.23, 5.41), and fetal weight growth restriction (RR 2.01, 95%CI: 1.03, 3.92) neonates after adjusting for maternal age, education, smoking during pregnancy, pre-pregnancy BMI, and gestational diabetes. Women with sleep deprivation (≤5 hours sleep) were at high risk for preterm births (RR 2.01, 95%CI: 1.24, 3.25), with the highest risk observed for medically indicated preterm births (RR 3.39, 95%CI: 1.33, 8.67) after adjusting for maternal age, education, parity, smoking during pregnancy, pre-pregnancy BMI, and gestational hypertension. Conclusion: These findings suggest that snoring, and sleep deprivation during pregnancy could be associated with increased risk for intrauterine growth restriction, Public Health & Health Care Management Faculty of Medicine – University of Crete 7 and preterm births respectively. Further epidemiological and mechanistic evidence is needed. Key words : sleep disorders during pregnancy, snoring
Language Greek
Subject Adverse birth outcomes
During pregnancy
Intrauterine growth restriction
Obstetrics
Sleep deprivation
Sleep disorders
Snoring
Αρνητικές εκβάσεις τοκετού
Διαταραχές ύπνου στην κύηση
Πρόωροι τοκετοί
Ροχαλητό
Στέρηση ύπνου
Υπολειπόμενη ενδομήτρια ανάπτυξη
Issue date 2010-12-14
Collection   School/Department--School of Medicine--Department of Medicine--Post-graduate theses
  Type of Work--Post-graduate theses
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