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Home    Ανίχνευση υποδοχέων σωματοστατίνης στον αμφιβληστροειδή: διαλυτοποίηση και βιοχημικός χαρακτηρισμός του υποδοχέα  

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Identifier uch.med.phd//1994DIS0060
Title Ανίχνευση υποδοχέων σωματοστατίνης στον αμφιβληστροειδή: διαλυτοποίηση και βιοχημικός χαρακτηρισμός του υποδοχέα
Alternative Title Detection of the somatostatinergic receptors in the retina: solubilization and biochemical characterization of the receptor
Creator Liapakis, George N
Abstract The present study revealed the presence of specific binding sites for somatostatin in the rabbit retina. These were solubilized in an active form using the detergents, chaps and octyl-glucoside in the presence of additional phospholipids and glycerol. The physiochemical properties of the solubilized somatostatinergic receptors were examined. These revealed that the receptors are N-glycozylated proteins coupled to G-proteins, have different molecular weights(27-60kd)and two different pi values. The pharmacological as well as the physicochemical properties of the retinal somatostatinergic receptors sugget the presence of different receptor-subtypes.
Issue date 1994-06-01
Date available 1997-06-6
Collection   School/Department--School of Medicine--Department of Medicine--Doctoral theses
  Type of Work--Doctoral theses
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