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Home Απομόνωση, φασματοσκοπικός χαρακτηρισμός και χρήση συστατικών του φυτού Dittrichia viscosa στην αντιμετώπιση του παρασίτου της μέλισσας Varroa destructor

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Identifier

000314704

Title

Απομόνωση, φασματοσκοπικός χαρακτηρισμός και χρήση συστατικών του φυτού Dittrichia viscosa στην αντιμετώπιση του παρασίτου της μέλισσας Varroa destructor

Alternative Title

Isolation, structure elucidation and use of components from the plant Dittrichia Viscosa against the bee parasite Varroa Destructor

Author

Σοφού, Καλλιόπη Μιχαήλ

Thesis advisor

Κατερινόπουλος, Χαράλαμπος

Abstract

This thesis includes results on the isolation and identification of the active component from the extract of the leaves of Dittrichia viscosa, a shrub growing in the area of Crete, Greece. The plant is traditionally used by bee keepers as a means of controlling the parasite known as Varroa destructor, that causes varroosis, a serious disease of the common bee, Apis mellifera. The spectral study leading to the identification of the active component as a terpenoid known with the name of costic acid is presented, as well as data clarifying discrepancies on the NMR data of the compound that appear in the literature. In vivo assays indicated that costic acid acts against the parasite with high efficacy without any toxic effects on the common bee. Moreover, preliminary field tests indicated that no toxic effects were found in the bee hives after the experiments meaning that the honey produced by the bees is free of costic acid. The above results strongly suggest that costic acid may be used as the basic component for the formulation of an environmentally safe product that can be used against varoosis. The analysis of the components of the essential oil of Dittrichia viscosa is also presented in the thesis, and the data are compared to those of related studies reported in the scientific literature.

Physical description

iv, 87 σ. : εικ. ; 30 εκ.

Language

Greek

Subject

Apis mellifera

Dittrichia viscosa

Varroa destructor

costic acid

varroosis

Πανεπιστήμιο Κρήτης. Διατριβές.

Πανεπιστήμιο Κρήτης. Τμήμα Χημείας Μεταπτυχιακές εργασίες.