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Identifier

000385518

Title

Η καταπολέμηση ασθενειών μεταφερόμενων από το κουνούπι με δύο προσεγγίσεις : η οδός της παραδιαγένεσης, η οδός της οντολογίας

Alternative Title

Paratransgenesis and ontology driven informatic tools: two different approaches to fight mosquito-borne diseases

Author

Μητράκα, Ελβίρα

Thesis advisor

Λούης, Χρήστος

Abstract

The mosquito is one of the most dangerous organisms for the human, due to its ability to act as a vector to a multitude of diseases, e.g. malaria and dengue fever. There have been many attempts at combating those diseases in many decades, either looking at the problem from the side of the vector or from the side of the pathogen. Until recently, the main mode of defense against the vector was the use of insecticides, but we have reached a crucial point in the phenomenon of insecticide resistance. Thus, the scientific community is also starting to look into new avenues, one which is the method of paratransgenesis. Here, the suitability of Asaia sp. to act as an agent in this method was examined. In the last few decades the field of bioinformatics has come to aid in this field, through the development of a slew of IT tools and data bases, wherein the huge amounts of information that are constantly produced, can be stored. It is imperative that those tools can not only communicate with each other, but also with the data available right now, and in the future. The solution to this matter are ontologies. Having in mind all those facts, we decided to develop the ontology of dengue fever, so that it can act as a linchpin between all those tools.

Language

Greek

Subject

Asaia

Bacteria

Bioinformatics

Dengue fever

Vector

Βακτήριο

Βιοπληροφορική

Δαγκείος πυρετός

Φορέας