Your browser does not support JavaScript!

Home    Πρωτεϊνική μεταθέταση τύπου ΙΙΙ: Πρωταρχικός χαρακτηρισμός κυτταροπλασματικών παραγόντων  

Results - Details

Add to Basket
[Add to Basket]
Identifier uch.biology.msc//2001chalkiadaki
Title Πρωτεϊνική μεταθέταση τύπου ΙΙΙ: Πρωταρχικός χαρακτηρισμός κυτταροπλασματικών παραγόντων
Author Χαλκιαδάκη, Αγγελική
Thesis advisor Οικονόμου, Αναστάσιος
Abstract The Type III Secretion (TTS) machine is present in Gram negative pathogenic bacteria and it is used for straight forward delivery of pathogenic proteins into eucaryotic hosts. It is a complex machine, conserved among bacterial pathogens of plants and animals and homologous to the flagellum. The phytopathogenic Pseudomonas syringae pv. phaseolicola was used as model organism to study TTS. The enzymatic and oligomeric analysis of HrcN showed that it is a high rate ATPase and active as an oligomer of ~600kDa, a conformation that can also be detected in the cell. Trying to visualize complexes that the ATPase and/or the substrate participate, high molecular weight complexes and specifically TTS induced cytoplasmic proteins interacting with the the ATPase and/or the substrate appeared. The identity and the importance of these proteins remain to be found.
Language Greek
Issue date 2001-12-06
Collection   School/Department--School of Sciences and Engineering--Department of Biology--Post-graduate theses
  Type of Work--Post-graduate theses
Views 210

Digital Documents
No preview available

Download document
View document
Views : 2