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Identifier

000397967

Title

Το Εθνικό Σχέδιο Δράσης Προκρούστης για την αντιμετώπιση λοιμώξεων από πολυανθεκτικά gram αρνητικά παθογόνα στα Νοσοκομεία της Κρήτης

Alternative Title

Procrustes .National action plan to combat infections due to carbapenem-resistant.gram-negative pathogens in hospital in Crete

Author

Χαριτάκης, Αλέξανδρος

Thesis advisor

Γκίκας, Αχιλλέας

Abstract

Introduction: The indicators of Healthcare associated infections from carbapenem-resistant Gram negatives (CRGNs) have increased worldwide. Given the extended resistance of CRGNs in the newer antibiotics observed in Greece, the Hellenic Center for Disease Control and Prevention (HCDCP), has developed a National Action Plan called “Procrustes” starting in 2010. Purpose: Determination of key epidemiological data of clinical infections from CRGNs in the context of the implementation of the National Action Plan "Procrustes" and recording the resistance of CRGNs to various last line antibiotics in hospitals in Crete. Methods: Starting in January 2011 through June 2015, specific clinical infections caused by CRGNs (Klebsiella, Pseudomonas, Acinetobacter) in hospitalised patients of the five largest public hospitals in Crete, were recorded in accordance with the criteria for infection of HCDCP. Results: 2180 clinical infection cases by CRGNs were recorded and overall crude mortality was 33.35%. Extended resistance to last line antibiotics, departments at high risk for infections (ICU, Medical wards) and specific infections with high rates of crude mortality (respiratory tract infections and bloodstream infections) were recorded. Discussion: The incidence of infections by CRGNs in hospitals in Crete is high and therapeutic options are limited in less than two classes of antibiotics. Early detection and prevention of healthcare associated infections can be Δημόσια Υγεία & Διοίκηση Υπηρεσιών Υγείας Τμήμα Ιατρικής – Πανεπιστήμιο Κρήτης 2 achieved by active surveillance cultures and adherence to an infection control program that includes separation of carriers and infected patients from non-carriers and strict implementation of contact precautions.

Language

Greek

Subject

Carbapenem resistance

Αντοχή στις καρβαπενέμες

Νοσοκομειακή λοίμωξη

Issue date

2015-12-18

Collection

School/Department--School of Medicine--Department of Medicine--Post-graduate theses

Type of Work--Post-graduate theses

Views

433

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