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Home    Ανάπτυξη Μεθόδου Υπερφασματικής Απεικόνισης για την in vivo καταγραφή και ανάλυση της κινητικής της αλληλεπίδρασης ασθενών οξέων και ιστών: Εφαρμογή στην διάγνωση καρκινικών και προκαρκινικών αλλοιώσεων.  

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Identifier uch.chemistry.msc//2002fragkouli
Title Ανάπτυξη Μεθόδου Υπερφασματικής Απεικόνισης για την in vivo καταγραφή και ανάλυση της κινητικής της αλληλεπίδρασης ασθενών οξέων και ιστών: Εφαρμογή στην διάγνωση καρκινικών και προκαρκινικών αλλοιώσεων.
Creator Fragkouli, Despina
Abstract The diagnostic method proposed in this project is based on the quantitative and objective assessment of the acetic acid-tissue. For the purpose of this study a Multispectral Imaging Spectroscopy system has been used. The method relies on the in vivo quantitative assessment of the spectral, spatial and temporal alterations of light-scattering properties induced in epithelial dysplasias and malignancies after topical application of acetic acid solution, (acetowhitening). The study of the temporal characteristics of the backscattered light indicates that there are significant differences between normal and abnormal epithelial areas, clearly manifested in the parameters of the kinetic of the phenomenon. Furthermore, this method is capable of the spatial imprinting of the abovementioned parameters by means of pseudocolor. In this way the quantitative mapping and the accurate specification of the lession’s limits is possible. Experimental data were analyzed using a model which describes the interaction of the acetic acid with the epithelial tissue which contains significant information about the morphological, structural and functional characteristics.
Subject Spectroscopy, Imaging, Malignancy, Acetowhitening, Pseudocolor, Mapping, Φασματοσκοπία, Απεικόνιση, Κακοήθεια, Αλλαγή Ιδιοτήτων Σκέδασης, Ψευδοχρώματα, Χαρτογράφηση
Issue date 2002-11-01
Date available 2002-12-06
Collection   School/Department--School of Sciences and Engineering--Department of Chemistry--Post-graduate theses
  Type of Work--Post-graduate theses
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