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Home    Πρότυπο έκφρασης του γονιδίου Gt12 στο κεντρικό νευρικό σύστημα του ποντικού σε εμβρυικά στάδια ανάπτυξης και στο ενήλικο άτομο  

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Title Πρότυπο έκφρασης του γονιδίου Gt12 στο κεντρικό νευρικό σύστημα του ποντικού σε εμβρυικά στάδια ανάπτυξης και στο ενήλικο άτομο
Creator Vidaki, Marina
Abstract Recent work has uncovered a large number of imprinted genes, many of which are thought to play a role in neurodevelopment and behavior. In order to begin to understand the role of specific genes in these processes, their expression patterns will be the key to their functional elucidation. In this study we used in situ hybridization to study the developmental expression of Gtl2 in the mouse central nervous system (CNS) from E10.5 to adulthood, since preliminary data from a microarray study indicated differential expression between the ventral and dorsal telencephalon of the mouse at a critical time point in the generation and migration of cortical neuronal populations. Strong expression was observed in the diencephalon, ventral telencephalon, post mitotic cell layers of the neocortex and pyramidal cell layer of the hippocampus.
Language Greek
Issue date 2005-12-01
Date available 2006-10-25
Collection   School/Department--School of Medicine--Department of Medicine--Post-graduate theses
  Type of Work--Post-graduate theses
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