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Identifier |
000310666 |
Title |
Νανοδομές σε συστήματα αισθητήρων και βιοαισθητήρων |
Alternative Title |
Nanostructures in sensors and biosensors |
Author
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Βαμβακάκη, Βασιλική Δημήτριος
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Thesis advisor
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Χανιωτάκης, Νικόλαος
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Abstract |
Recent advances in the field of nanotechnology has enabled the development and evaluation of nano-systems based on novel nanomaterials that offer new directions in the field of bio-analytical systems. Research efforts are mainly focused on the stabilization of enzymes in nanoporous materials with pores or internal spaces in the range of nanometers. Nanoporous materials are more exciting candidates for enzyme immobilization compared with conventional materials due to their large surface area and opened pore structure that allows high enzyme loading. Moreover the size matching between the pore size of the nanomaterials and the molecular diameter of the enzymes seems to provide a stabilizing effect to the immobilized enzymes.
In this study enzyme immobilization in nanoporous silica beads with well controlled pore sizes is evaluated in order to verify the stabiliation effect of immobilization. Also enzyme stabilization in the nanoenvironment of liposomes is examined. The aim of the project is the introduction of the nanomaterials-biomolecules complexes in biosensor systems for the development of advanced analytical techniques that allows for reliable quantitative and qualitative analysis.
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Language |
Greek |
Subject |
Biosensors |
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Enzyme stabilization |
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Liposomes |
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Nanoporous silica beads |
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Βιοαοσθητήρες |
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Λιποσώματα |
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Νανοπορώδη σφαιρίδια διοξεδίου του πυριτίου |
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Σταθεροποίηση ενζύμων |
Issue date |
2004 |
Collection
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School/Department--School of Sciences and Engineering--Department of Chemistry--Post-graduate theses
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Type of Work--Post-graduate theses
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Views |
185 |