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Home    Μελέτη του φαινοτύπου των TAG-1 ελλειπτικών μυών και διερεύνηση του ρόλου της TAG-1 στη μετανάστευση των ολιγοδενδροκυττάρων  

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Title Μελέτη του φαινοτύπου των TAG-1 ελλειπτικών μυών και διερεύνηση του ρόλου της TAG-1 στη μετανάστευση των ολιγοδενδροκυττάρων
Creator Trichas, Georgios
Abstract The development of the central neural system consists of complex cellular procedures including cell migration. The developing neurons migrate from their place of birth to their final destination in two directions: radially and tangentially. During the migration, the neural cells are guided by signal molecules which are proteins that act in an attractive or repulsive way. The combination of these proteins constitutes the guidance mechanism and defines the migration pattern the migrating neurons will follow. Like the neurons, the interactions between endogenous and exogenous signals induce the differentiation of the oligodendroglial lineage. In mouse, the oligodendrocyte precursors are born in the ventral part of the ventral neural tube at the age of Ε9.5, Ε10 and onwards, and migrate rostrally. This rostral migration could be affected by the above interactions.
Language Greek
Issue date 2006-03-01
Date available 2006-11-23
Collection   School/Department--School of Medicine--Department of Medicine--Post-graduate theses
  Type of Work--Post-graduate theses
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