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Home    Σχέση κυτταρικού πολλαπλασιασμού και απόπτωσης με ανοσοϊστοχημική μελέτη σε FNA παρασκευάσματα διηθητικών πορογενών νεοπλασμάτων του μαστού  

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Identifier 297540
Title Σχέση κυτταρικού πολλαπλασιασμού και απόπτωσης με ανοσοϊστοχημική μελέτη σε FNA παρασκευάσματα διηθητικών πορογενών νεοπλασμάτων του μαστού
Creator Antoniou, Chara
Abstract The purpose of this study was to investigate cell proliferation and apoptosis in ductal breast invasive carcinomas and their relationship to prognosis. Fifty cases, from the same number of operable female patients, were diagnosed cytologically on ΦΝΑ biopses as invasive ductal carcinomas and confirmed histologically after oncectomy. In the same cases, to evaluate the cell proliferation and apopsis, the MIBI and the TUNEL method were used respectively. Furthermore the relationship between proliferative activity and apoptosis to other factors such as menopausal status, tumor size, axillary lymph node status and tumor grade was studied. Cell proliferation and apoptosis were found to be significantly related to the menopausal status of the patients(p<0,001) and to the grade of the tumor (p<0,01), while no significant relationship to axillary lymph node status and tumor size was found
Language Greek
Issue date 2004-12-01
Date available 0000-00-01
Collection   School/Department--School of Medicine--Department of Medicine--Doctoral theses
  Type of Work--Doctoral theses
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