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| Identifier |
000410281 |
| Title |
Θνησιμότητα και νοσηρότητα από καρκίνο του μαστού στην Κρήτη, 1992--2013. : Επιιδημιολογικοί δείκτες στο χώρο και το χρόνο |
| Alternative Title |
Mortality and incidence of breast cancer in Crete, 1992-2013. |
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Author
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Κοτζαμάνη, Αργυρώ
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Thesis advisor
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Λιονής, Χρήστος
Μαυρουδής, Δημήτριος
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| Abstract |
Aim: Breast cancer (BC) is the second cause of death for females according to global data. In
2012, 522.000 people lost their lives due to BC. This study aims to estimate the “burden” of
the disease in Crete in incidence and mortality rates and detect the high risk municipalities in
order to take preventive measures.
Method: Data were obtained from the Cancer Registry Center (CRC) regarding all cases of BC
for the period 1992-2013.The following rates were estimated of Crete, Αge-Standardized
Incidence Rates (ASIR), Age-Specific Incidence Rates (ASpIR), Age-Standardized Mortality
Rates (ASMR), Age-Specific Mortality Rates (ASpMR). The automatic processes of the CRC’s
monitoring system (connected to STATA software and ArcGIS 10.3) were utilized to calculate
the above rates and illustrate them in graphs and tables (all tests were conducted at a
significance level of 0.05). Spatio-temporal trends and CC hot spots were estimated using the
Getis Ord G *. Bayesian age-period-cohort prediction model was used for the estimation of
the expected incidence and mortality rates (2014-2023).
Results: For the study period (1992-2013) incidence and mortality showed an increasing
trend. Specifically, mean ASIR was 56.5/100.000/year and mean ASMR was
19.9/100.000/year. Age groups 65-69 and 80-84 presented the highest rates of Age-Specific
Incidence Rate (ASIR=389.5/100.000/year and ASIR=395.2/100.000/year). Five-year survival
rate of BC was 87.9% and ten-year survival rate was 78.1%. Risk factors that were identified
include personal history of cancer, family history of BC or other cancer, degree of
relationship and smoking. Most municipalities of Crete are high risk areas for BC, while
differences were detected in incidence and mortality rates, and annual rate change among
them.
Conclusion: BC incidence and mortality in Crete during 1992-2013 was increasing,. Future
trends indicate further increase probably due to the lifestyle of the residents, economic crisis
and inadequate preventive measures. These data should be further examined and
preventive measures to reduce the disease “burden” should be taken.
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| Language |
Greek |
| Subject |
cancer registry center |
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κέντρο καταγραφής καρκίνου |
| Issue date |
2017-07-26 |
| Collection
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School/Department--School of Medicine--Department of Medicine--Post-graduate theses
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Type of Work--Post-graduate theses
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| Views |
366 |
Θνησιμότητα και νοσηρότητα από καρκίνο του μαστού στην Κρήτη, 1992--2013. : Επιιδημιολογικοί δείκτες στο χώρο και το χρόνο
