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Title

Fabrication and characterization 3-D tissue-like phantoms with controllable optical and acoustic properties

Alternative Title

Παρασκευή και χαρακτηρισμός 3-D ομοιωμάτων ιστών με ελεγχόμενες οπτικές και ακουστικές ιδιότητες

Author

Επιτροπάκη, Κωνσταντίνα

Abstract

The interest in manufacturing 3D tissue-like phantoms by using different materials has increased dramatically during the last decades. Generally, phantoms can be considered very useful devices either for system calibration or for algorithm optimization. Moreover, tissue equivalent phantoms can be developed with controllable optical, mechanical or even structural properties. Thus, such phantoms can be used as substitutes in order to reduce to a minimum the use of animals during the experimental periods. The goal of this study is to fabricate homogeneous phantoms that match the optical and mechanical characteristics of tissues in the visible and near-infrared spectral range. In this study, the basic phantom material for phantom manufacturing is PVCP. This material has been purposefully selected since it has been used in previous studies for characterization of absorption, scattering at single and multiple wavelengths and definition of speed of sound. In this project, each sample was measured for its optical absorption using spectrophotometer or wavelengths from 500nm up to 1700nm, for the speed of sound by applying the photoacoustic effect at 5MHz and finally was characterized for its rheological properties by using a rheometer with isothermal frequency scans from 10^-1 rad/sec to 10² rad/sec.

Language

Greek

Subject

Photoacoustic effect

Reology

Speed of sound

Ρεολογία

Ταχύτητα ήχου

Φωτοακουστικό φαινόμενο

Issue date

2017-07-21

Collection