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Title Optimization and characterization of photoacoustic microscopy in reflection mode geometry
Author Ανδρεαδάκη, Ελένη
Thesis advisor Ζαχαράκης, Ιωάννης
Abstract Biomedical scientists have developed a variety of optical systems in different geometries and with a variety of characteristics that basically use the photoacoustic effect for imaging. This work was focused on the creation of such a system in reflection mode geometry. The main aim was the optimization and characterization of the set up after its construction. In more detail, firstly it was decided which kind of photoacoustic microscopy would be used, OR-PAM or AR-PAM. Later after making the choice of using the OR-PAM it was studied how the acoustic (transducer) and optical (objective) components would be combined in order to be able to produce a high acoustic signal. Furthermore after the selection of the appropriate combination, the next step was the improvement of the signal by choosing a suitable acoustic lens in front of the detector which would guide the ultrasound on the transducer. In addition it was taken under consideration which geometries of ultrasound transmission were more efficient, the use of a beam splitter or an ultrasound reflecting glass. Also after acquisition of the clear signal the characteristics of the modality, such as the typical value of the photoacoustic signal (Vpp), the signal to noise ratio, the frequency range of the transducer and lastly the field of view were determined. Finally the first images of the system with the help of phantoms were taken.
Language English
Issue date 2023-03-31
Collection   School/Department--School of Sciences and Engineering--Department of Physics--Graduate theses
  Type of Work--Graduate theses
Permanent Link https://elocus.lib.uoc.gr//dlib/b/a/3/metadata-dlib-1677656778-496634-27959.tkl Bookmark and Share
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