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Title Morphology and viscoelasticity of fibrilar collagen -based formulations for regenerative medical applications
Alternative Title Ρεολογία, κολλαγόνο ικρώματα, αιωρήματα, ίνες αναγεννητική ιατρική μικροσκοπία, γέλες
Author Λυρώνη, Κων/να
Thesis advisor Βλασσόπουλος, Δημήτριος
Cloitre, Michel
Abstract Nowadays, regenerative medicine has increasingly appealing to the scientific community as it provides all the necessary supplies for the regeneration of damaged living matter, from a part of tissue, to the regeneration of an entire organ. In this thesis, we will delve into the morphology and the viscoelasticity of fibrillar collagen-based suspensions that are utilized in regenerative medicine scaffolds. Although literature emphasizes on collagen type I hydrogels, limited information is available on porous scaffolds made of lyophilized fibrillar suspensions of collagen type I despite their established utilization in regenerative medicine grafts. The raison d’ être of this thesis is to have a new perspective of collagen suspensions in terms of morphology and viscoelasticity. For this purpose, various microscopy methods such as phase contrast microscopy and cryo-TEM have been used in order to get more information on the morphology of these suspensions, as well as rheological methods to combine the imaging with the rheological response of the suspensions
Language English
Issue date 2022-07-29
Collection   School/Department--School of Sciences and Engineering--Department of Materials Science and Technology--Graduate theses
  Type of Work--Graduate theses
Permanent Link https://elocus.lib.uoc.gr//dlib/6/a/8/metadata-dlib-1665385914-599724-32726.tkl Bookmark and Share
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