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Identifier uch.med.phd//1998zoumakis
Title Μελέτη της έκφρασης, της ρύθμισης και του βιολογικού ρόλου της oρμόνης έκλυσης της κορτικοτροπίνης (CRH) στο ανθρώπινο ενδομήτριο
Alternative Title Expression, regulation and biological role of endometrial corticotropin releasing hormone (CRH)
Creator Zoumakis, Emmanouel N
Abstract Εpithelial cells of human and rodent endometrium express the corticotropin-releasing hormone (CRH) and opioid peptide precursors genes, i.e. proopiomelanocortin, proenkephalin and prodynorphin and releases their end-products. Normal stromal cells of the endometrium do not seem to express CRH unless they differentiate to decidual cells. These endometrial neuropeptides are under the control of steroid hormones, prostanoids and interleukins. Considering the involvement of CRH in pro-inflammatory phenomena it is postulated that endometrial CRH, in association with uterine prostanoids/cytokines and opioids, may participate in intrauterine inflammatory processes of early pregnancy, such as stroma decidualization and blastocyst implantation.
Issue date 1998-07-01
Date available 1998-06-2
Collection   School/Department--School of Medicine--Department of Medicine--Doctoral theses
  Type of Work--Doctoral theses
Permanent Link https://elocus.lib.uoc.gr//dlib/5/d/0/metadata-dlib-1998zoumakis.tkl Bookmark and Share
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