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Title Οροεπιδημιολογική συγκριτική μελέτη μεταξύ ολικών και εξουδετερωτικών αντισωμάτων για το ιό SARS-CoV-2 στον πληθυσμό της Κρήτης.
Author Κισσανδράκη, Εμμανουέλα
Thesis advisor Γεώργιος Χαλεπάκης
Γεώργιος Σουρβίνος
Abstract Covid-19 constitutes one of the most challenging pandemics the global community faces in the 21st century. It is a highly infectious disease that affects the respiratory system and is caused by the SARS-CoV-2 virus, a constituent of the RNA virus family, which emerged for the first time in Wuhan, China, in December 2019. The COVID-19 pandemic has undeniably brought serious consequences to various aspects of society and for this reason, to mitigate the risk to public health, governments have undertaken non-pharmaceutical interventions such as mask-wearing, quarantines, etc., to curtail the spread of infection, reduce viral load, and ensure sufficient time for the development of vaccines and treatments. In addition to the preceding measures, a pivotal factor in pandemic management has been the utilization of seroepidemiological studies, which serve to enable scientists to comprehend the propagation of the virus, assess population immunity, and ascertain the effectiveness of vaccines. To achieve the foregoing objectives, researchers undertake, via seroepidemiological investigations, an analysis of the antibodies developed by patients against the nucleocapsid and spike proteins of the virus. We conducted a study to evaluate the levels of specific antibodies, including neutralizing antibodies, which are crucial for immediate prevention and treatment of virus infections. Participants from eight different health facilities (hospitals and health centres) in Crete were included in the study, and the analysis of antibody levels was conducted using the ELISA method in an immunological analyzer. The study provided an initial picture of the immunological status due to vaccination and natural infection in the population of Crete during the period when the Omicron variant was prevalent, based on seroepidemiological data and analyses conducted.
Language Greek
Subject Neutralizing antibodies
Nucleocapsid protein
Omicron variant
Protein Spike
Vaccination
Εμβολιασμός
Εξουδετερωτικά αντισώματα
Μετάλλαξη Όμικρον
Νουκλεοκαψίδιο
Πρωτεΐνη S
Issue date 2024-03-29
Collection   School/Department--School of Sciences and Engineering--Department of Biology--Graduate theses
  Type of Work--Graduate theses
Permanent Link https://elocus.lib.uoc.gr//dlib/a/4/1/metadata-dlib-user1709152601-18251.tkl Bookmark and Share
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