Post-graduate theses
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Identifier |
000373494 |
Title |
Συγκριτική αξιολόγηση τεχνικών ακτινοβόλησης στην τρισδιάστατη σύμμορφη ακτινοθεραπεία:Εκτίμηση της δόσης και του αντίστοιχου ακτινογενή κινδύνου στα υγιή όργανα |
Alternative Title |
Comparative analysis of irradiation techniques in three-dimentional conformal radiotherapy :Evaluation of dose and respective radiogenic riskat organs -at-risk. |
Author
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Πέππα, Βασιλική
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Thesis advisor
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Δαμηλάκης, Ι.
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Reviewer
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Μαζωνάκης, Μ.
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Abstract |
The aim of the current study was to compare different irradiation techniques in threedimensional
conformal radiotherapy, so as to evaluate the optimum technique
regarding the local tumor control and sparing of normal tissues. The anatomical
structures that were examined were prostate, urinary bladder, brain, parotid gland,
breast and stomach. In the first four structures, radiotherapy was administered in two
phases. Specific treatment techniques were chosen in each treatment phase, according
to the examined anatomical structure. The goal was to find the most appropriate
combination of irradiation techniques in the two treatment phases, in point of TCP,
NTCP, UTCP and mean dose of each organ-at-risk. In terms of breast and stomach,
radiotherapy was administered in one treatment phase. The evaluation of different
irradiation techniques in each structure was performed considering the coverage of
PTV and mean dose at critical organs. In highly radiosensitive organs the stochastic
risk was also estimated. The results of this study showed that the inspection of the
optimum combination of irradiation techniques in different treatment phases is
necessary to be incorporated in routine clinical practice. In breast, the threedimensional
irradiation techniques diminished the deterministic and stochastic risk
factors at healthy tissues, comparing to standard irradiation technique in twodimensional
conventional radiotherapy. In stomach, the results of this study are
encouraging concerning the deterministic side effects at organs-at-risk
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Language |
Greek |
Subject |
Brain |
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Breast |
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Irradiation techniqueprostate |
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Parotid |
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Radiology |
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Stomach |
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Three-dimensional comformal radiotherapy |
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Urinary bladder |
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Εγκέφαλος |
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Μαστός |
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Ουροδόχος κύστη |
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Παρωτίδα |
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Προστάτης |
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Στομάχι |
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Τεχνική ακτινοβόλησης |
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Τρισδιάστατη σύμμορφη ακτινοθεραπεία |
Issue date |
2010-07-20 |
Collection
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School/Department--School of Medicine--Department of Medicine--Post-graduate theses
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Type of Work--Post-graduate theses
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Permanent Link |
https://elocus.lib.uoc.gr//dlib/d/9/f/metadata-dlib-1334051776-317548-14514.tkl
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Views |
183 |