Post-graduate theses

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Identifier	000404511
Title	Ο Καρκίνος του στόματος στην Κρήτη : Επιδημιολογικά δεδομένα του αρχείου καταγραφής καρκίνου την περίοδο 1992-2013
Alternative Title	The oral cancer in Crete
Author	Φραγκιαδάκης, Εμμανουήλ
Thesis advisor	Τζανάκης, Νικόλαος Λιονής, Χρήστος Βλασιάδης, Κων/νος
Reviewer	Σηφάκη-Πιστόλλα, Δήμητρα
Abstract	Aim: Cancer is one of the leading causes of death worldwide, with 8.2 million deaths in 2012. Oral cancer (OC) is the sixth most common type of cancer worldwide and during the last decade it presents an increasing trend especially among women. The purpose of this study is to assess the oral cancer burden in Crete in terms of morbidity and mortality rates, and to propose interventions in high risk municipalities and populations. Material-Methods: This study is part of the regional Cancer Registry of Crete (CRC) activities. Data were obtained from the CRC’s database regarding new cases and deaths from oral cancer during the period 1992-2013 in Crete (8 hospitals, 23 death registries) . The Age-Standardized Incidence Rates (ASIR/ 100,000 / year) and the Age-Standardized Mortality Rates (ASMR/100,000/year) were estimated. Convensional and spatial statistics were performed at a level of significance of 0.05. Results: The Mean AAIR for the period 1992-2013 was 1.61/100,000/year (ASIR men = 2/100,000/year, ASIR women 1.4/100,000/year), while the average ASMR was 0.78 /100,000/year (ASMR men = 0.9/100,000/year, ASMR women = 0.69 / 100,000 / year). Five (5) years after diagnosis of OC, the survival of the population was 88.1%. The risk of death in smokers was 2.9 times higher than in non-smokers (P-value = 0.02), while alcohol consumers presented 1.3 times greater risk (P-value 0.03). Among municipalities there were no significant variations, but some municipalities presented higher OC burden. Conclusions: The findings of this study revealed factors that potentially affect the appearance of OC which seems to steadily increase in Crete. This information can contribute to the design of «field studies» and actions to inform population groups and areas in risk
Language	Greek
Issue date	2017-12-13
Collection	School/Department--School of Medicine--Department of Medicine--Post-graduate theses
	Type of Work--Post-graduate theses
Permanent Link	https://elocus.lib.uoc.gr//dlib/e/d/8/metadata-dlib-1484134412-361380-17530.tkl
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