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Identifier 000444078
Title An inception cohort study of patients with Incomplete Lupus Erythematosus progressing or not to Systemic Lupus Erythematosus : Identification of environmental, serologic and clinical predictors linked to early diagnosis and prognosis
Alternative Title Προοπτική μελέτη ασθενών με ατελή Συστηματικό Ερυθηματώδη Λύκο που μεταβαίνουν ή όχι σε Συστηματικό Ερυθηματώδη Λύκο
Author Εμμανουηλίδου, Ευγενία
Thesis advisor Μπερτσιάς, Γεώργιος
Abstract Pre-Systemic Lupus Erythematosus (pre-SLE) encompasses a broad range of presentations, spanning from asymptomatic individuals with immunological abnormalities to individuals with autoantibodies and some features suggestive of SLE who do not yet meet the classification criteria. Research on this topic could reveal predictive or diagnostic biomarkers for individuals “at high” risk for progression to SLE. Herein, we present the results of an ongoing prospective pre-SLE cohort of the Rheumatology Clinic at the University Hospital in Heraklion Crete. The environmental, serological and clinical characteristics of incomplete lupus erythematosus (ILE) patients are outlined. The primary goal of the study is to identify “at risk” individuals for SLE transition and characterize biomarkers of early disease. This will allow for close monitoring and implementation of early interventions to delay disease onset and organ inflammation/ damage.
Language English
Issue date 2021-12-01
Collection   School/Department--School of Medicine--Department of Medicine--Post-graduate theses
  Type of Work--Post-graduate theses
Permanent Link https://elocus.lib.uoc.gr//dlib/3/e/0/metadata-dlib-1639129025-89144-1767.tkl Bookmark and Share
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