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Identifier

000426224

Title

ProteoSign 2.0 : A differential expression analysis tool for Proteomics data

Alternative Title

Proteosign 2.0

Author

Θεοδωράκης, Ευάγγελος

Thesis advisor

Ηλιόπουλος, Ιωάννης

Abstract

Bottom-up proteomics analyses have been proved to be a powerful tool in the characterization of the proteome. Through differential proteomic analysis one can shed light on groups of proteins or individual proteins that give rise to various conditions -normal or pathological. However the tools for the analysis of such data sets are either hard-to-use with steep learning curves although powerful, or easy to use, but lack the analytical power of others. In order to cope with these challenges, we present ProteoSign 2.0, the upgrade of ProteoSign, a tool for differential proteomic analysis for proteomics datasets coming from MaxQuant or Proteome Discoverer™.

Language

English

Subject

Bioinformatics

Data analysis

Linear models

Ανάλυση δεδομένων

Βιοπληροφορική

Γραμμικά μοντέλα

Πρωτεωμική

Issue date

2019-12-11