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Identifier

000369757

Title

Μελέτη επιπολασμού των νοσοκομειακών λοιμώξεων σε τριτοβάθμιο νοσοκομείο.

Alternative Title

Prevalence study of nosocomial infections in a tertiary care hospital

Author

Μπολίκας, Εμμανουήλ

Thesis advisor

Γκίκας,Αχιλλέας

Reviewer

Ρουμπελάκη, Μαρία

Abstract

OBJECTIVE. To estimate the prevalence of nosocomial infections (NI) and antibiotic use in a tertiary care hospital. METHODOLOGY. A point prevalence study was conducted in the University Hospital of Heraklion (July 2010), within the framework of the hospitals’ participation in the development and pilot implementation of a common European protocol initiated by the European Centre for Disease Prevention and Control (ECDC). All inpatients in 25 hospital departments were surveyed to obtain demographic and clinical data, and data regarding NI and antimicrobial usage. RESULTS. A total of 54 NIs were detected in 43 of the 456 surveyed patients. The prevalence rate of patients with at least one NI was 9.4% (95% confidence interval [CI]: 6.9% - 12.5%), while the prevalence of NI was 11.8 cases per 100 patients (95%CI: 9.0 to 15.2). The most frequent infections were bloodstream infections (3.3 cases per 100 patients; 95%CI: 1.9-5.4), followed by urinary tract infections (2.2%; 95% CI: 1.1-4.0), pneumonias (2.0%; 95%CI: 0.9-3.7), and surgical site infections (1.3%; 95%CI: 0.5-2.8). The leading pathogens were Acinetobacter species (19,2%), Pseudomonas aeruginosa (19,2%) and Enterococcus species (13.5%). Overall, 235 patients (51.5%; 95%CI: 46.8 - 56.2) received 351 antibiotics. The most frequent indication for antibiotic use was the treatment of a community-acquired or a nosocomial infection (for 25.9% of the surveyed; 95%CI: 21.9-31.2), followed by Public Health & Health Care Management Faculty of Medicine – University of Crete 4 medical prophylaxis (12.7%; 95%CI: 9.8-16.1) and surgical prophylaxis (12.5%; 95%CI: 9.6-15.9). The duration of surgical prophylaxis was >1 day for 80.7% of the patients who received it. CONCLUSIONS. The prevalence of patients with NI in the study hospital lies within the range observed in most European countries, but there is considerable room for improvement. A markedly high prevalence of antibiotic use was recorded, stressing an urgent need to develop more effective strategies to control the usage of these drugs. The data obtained in this study highlighted infection control areas that require immediate corrective actions and provided specific targets for intervention.

Language

Greek

Subject

Antibiotic use

Hospital

Nosocomial infection

Prevalence

Surveillance

Επιπολασμός

Επιτήρηση

Νοσοκομειακή λοίμωξη

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