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Identifier 000461792
Title Eye movement-based analysis in reading : A method for evaluating functional vision in normal ageing,presbyopia correction and in retinal diseases
Alternative Title Ανάλυση οφθαλμικών κινήσεων κατά τη διάρκεια ανάγνωσης
Author Κτιστάκης, Εμμανουήλ
Thesis advisor Τσιλιμπάρης, Μιλτιάδης
Σίμος, Παναγιώτης
Δετοράκης, Ευστάθιος
Reviewer Σιγανός, Χαράλαμπος
Τσικνάκης, Μανόλης
Μουζάκη, Αγγελική
Κρασανάκης, Βασίλειος
Abstract Visual acuity assessment is the preferred first-line test among clinicians to evaluate the integrity of the visual system. However, simple measures of near acuity, while of interest, may provide only a partial indication of functional vision and of the effectiveness of surgical or optical corrections. Since many activities of daily living rely on reading it is not surprising that reading difficulty is the most common complaint among individuals with decreased vision, while it forms the primary reason for patients to seek referral to a low vision clinic and a strong predictor of vision-related quality of life. Reading, however is a complex function. It requires a proper retinal image and intact retina to send information to the brain, where the image is analyzed for extraction of meaning. Thus it is difficult to evaluate functional vision based on reading performance. The evolution of eye trackers, new standardised reading tests and computational and statistical methods have given valuable tools to further analyse reading performance through eye movement parameters. The aim of this work is to use eye movement analysis during text reading to evaluate functional vision under different conditions. It is divided into four studies involving: assessment of method repeatability, applications to age-related macular disease, anti-VEGF treatment, and presbyopia correction, as well as the study of reading comprehension. A secondary aim is to find certain eye movement parameters that are distinctly affected under each condition and factor. In this context, the ex-Gaussian analysis is used to evaluate the fixation duration distribution. The results highlight certain distinct effects of specific factors on eye movement and ex- Gaussian parameters. Ex-Gaussian parameter τ, the percentage of regression and the number of forward fixations were affected by cognitive (higher-level) processes while ex-Gaussian μ, fixation duration and the number of fixations were mainly affected by optical (lower-level) factors. In the future, studies of specifically manipulated changes in certain factors have to be performed. More refined computational methods and machine learning approaches could provide more thorough analysis of eye movement parameters during reading.
Language English
Subject Οφθαλμικές κινήσεις
Issue date 2024-04-17
Collection   School/Department--School of Medicine--Department of Medicine--Doctoral theses
  Type of Work--Doctoral theses
Permanent Link https://elocus.lib.uoc.gr//dlib/6/7/2/metadata-dlib-1706009647-527608-30710.tkl Bookmark and Share
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