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Identifier 000028051
Title Σύνθεση και μελέτη ντοπαμινεργικής και α-αδρενεργικής δραστικότητα αναλόγων της ντοπαμίνης
Alternative Title Sythesis and dopaminergic and α-adrenergic activity of dopamine analogs
Author Ταγματάρχης, Νίκος Ι
Thesis advisor Κατερινόπουλος, Χαράλαμπος
Abstract Ιn this doctoral dissertation is descriped the methodology for the synthesis of a series of catechelamines analogys and the ekucidation of their invitro activity in Dopaminergic and α-Adremergic agento. The thesis is presented in two parts. The first includes thw sythetic and biological activity studies of β -Aleoxy substituted Aryl-ethylamine analogs. The second part includes studies on Octahydrobenzo (f) -and- (g) quinoline analogs. The results of the invitro biological studies of these compounds are discussed in the basis of the relationship between their structural features and their activity profile at the Dopaminergic and α Adrenergic receptors.
Language Greek
Subject Activity profile
Catecholamines
Dopaminergic activity
Synthesis octahydrobenzo(f)-and-(g)quinolines
Synthesis β-alcoxy substituted aryl-ethyalamines
in vitro activity
in vitro δραστικότητα
Δομικά χαρακτηριστικά δραστικότητας
Κατεχολαμίνες
Ντοπαμινεργική δραστικότητα
Σύνθεση β-αλκόξυ υποκατεστημένων
Σύνθεση οκταϋδροβενζο(f)-και-(g)κινολινών
α- adrenergic activity
α- αδρενεργική δραστικότητα
Issue date 1997-09-01
Collection   School/Department--School of Sciences and Engineering--Department of Chemistry--Doctoral theses
  Type of Work--Doctoral theses
Permanent Link https://elocus.lib.uoc.gr//dlib/c/1/d/metadata-dlib-1997tagmatarxis.tkl Bookmark and Share
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