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Identifier https://doi.org/10.3390/jcm13123461
Title Recurrent urinary stone formers: imaging assessment and endoscopic treatment strategies: a systematic search and review
Author Mavridis, Charalampos
Author Bouchalakis, Athanasios
Author Tsagkaraki, Vasiliki
Author Somani, Bhaskar Kumar
Author Mamoulakis, Charalampos
Author Tokas, Theodoros
Publisher MDPI: J. Clin. Med. 2024, 13(12), 3461
Abstract Background/Objectives: Nephrolithiasis is a heterogeneous disease with a high prevalence and recurrence rate. Although there has been much progress regarding the surgical treatment of stones, a standardized follow-up, especially in recurrent stone formers (SFs), has yet to be decided. This fact leads to the overuse of computed tomography (CT) scans and many reoperations in patients, thus increasing their morbidity and the financial burden on the health systems. This review systematically searched the literature for original articles regarding imaging strategies and endoscopic treatment for patients with recurrent urolithiasis, aiming to identify optimal strategies to deal with these patients. Methods: We systematically searched the Medline database (accessed on 1 April 2024) for articles regarding imaging modalities and endoscopic treatment for patients with recurrent urinary tract lithiasis. Results: No specific follow-up or endoscopic treatment strategy exists for patients with recurrent urolithiasis. CT scan was the imaging modality most used in the studies, followed by X-ray, ultrasonography, and digital tomosynthesis. A transparent algorithm could not be identified. Percutaneous nephrolithotomy (PCNL), retrograde intrarenal surgery (RIRS), and ureteroscopy (URS) were used in the studies for endoscopic treatment. PCNL showed the best stone-free (SFr) rate and lowest hazard ratio (HR) for reoperation. RIRS showed superiority over extracorporeal shockwave lithotripsy for recurrent SFs, but fragments over 4 mm increased the recurrent rate. URS has an increased HR for reoperation for bilateral stones. Conclusions: The heterogeneity of urolithiasis leaves urologists without a standardized plan for recurrent SFs. Thus, each patient’s follow-up should be planned individually and holistically. Pre-stenting is not to be avoided, especially in high-risk patients, and SFr status needs to be the aim. Finally, CT scans should not be generally overused but should be part of a patient’s treatment plan. Prospective studies are required to define SFr status, the size of significant residual fragments, and the modalities of intervention and follow-up.
Language English
Subject Kidney stones
Nephrolithiasis
PCNL
RIRS
Stone recurrence
URS
Urolithiasis
Issue date 2024-06-13
Collection   School/Department--School of Medicine--Department of Medicine--Publications
  Type of Work--Publications
Access Rights
Creative Commons License
Permanent Link https://elocus.lib.uoc.gr//dlib/a/b/e/metadata-dlib-1719391909-568132-17942.tkl Bookmark and Share
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