Results - Details
Search command : Author="Μαζωνάκης"
And Author="Μιχαήλ"
Current Record: 2 of 4
|
Identifier |
000430965 |
Title |
Αξιολόγηση ογκομετρικών μεθόδων για τον οφθαλμικό κόγχο |
Alternative Title |
Clinical applications of volumetric analysis in the human orbit |
Author
|
Μπόντζος, Γεώργιος
|
Thesis advisor
|
Δετοράκης, Ευστάθιος
|
Reviewer
|
Μαρής, Θωμάς
Μαζωνάκης, Μιχαήλ
Τσιλιμπάρης, Μιλτιάδης
Χλουβεράκης, Γρηγόρης
Ξεκούκη, Παρασκευή
Εφροσύνη, Παπαδάκη
|
Abstract |
Purpose: Orbital volume measurements comprise an essential clinical tool for
managing several morbidities of the orbital area. In the presented work, we
investigate methods that can provide precise measurements of the orbital volume
and its contents (eye globe, extraocular muscles, optic nerve). Furthermore, clinical
evaluation of these calculations is provided by examination of patients affected with
orbital disease.
Methods: We tested manual, semi-automated and fully automated methods for their
validity and repeatability in orbital, eyeball, muscle and nerve volumetry. Methods
were applied in computed tomography and magnetic resonance imaging series.
Estimations were expanded in patients with high myopia and hyperopia where there
is significant imbalance between eyeball position and orbital volume. Moreover,
patients affected by thyroid eye disease underwent volume measurements with a
view to evaluate extraocular muscle volume and disease status.
Results: Methods of manual planimetry and semi-automated stereology were
selected for further analysis regarding their validity. An algorithmic approach of
volume measurements for the orbit and its contents was set. In the clinical part of
this work, the effective orbital volume was measured in patients with high myopia
and clinical correlations between volumes and anthropometric variables were
examined. In patients affected by thyroid eye disease, 3D muscle volumetry was
performed and results were compared to standard 2D evaluation of muscle diameter
for estimating disease status.
Conclusions: The human orbit is prone to several pathologies including
inflammatory disease, tumors, congenital malformations and fractures of its walls.
Alterations in orbital volume can affect the harmonious anatomy between the fine
structures of the orbit and may manifest with symptoms such as exophthalmos,
enophthalmos and diplopia. Precise measurement of the orbital volume is of utmost
importance for performing orbital surgery, as vulnerable vessels and nerves can be damaged during surgical approach. In daily practice, orbital volume measurement is
often underestimated due to the laborious and time consuming methods. Objective
approaches are often used instead which may lead to inaccurate results. By applying
the systemic approach along with the presented algorithms we can achieve
meaningful results and minimize the required time for calculations.
|
Language |
Greek |
Subject |
Eye |
|
Skull |
|
Volume measurement |
|
Κρανίο |
|
Μέτρηση όγκου |
|
Οφθαλμός |
Issue date |
2020-08-05 |
Collection
|
School/Department--School of Medicine--Department of Medicine--Doctoral theses
|
|
Type of Work--Doctoral theses
|
Permanent Link |
https://elocus.lib.uoc.gr//dlib/4/6/c/metadata-dlib-1596705595-265234-29499.tkl
|
Views |
517 |