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Identifier 000399725
Title 3D reconstruction of cornea
Alternative Title Τρισδιάστατη ανοικοδόμηση του κερατοειδή
Author Γεωργιάδη, Λεονή
Thesis advisor Παναγοπούλου, Σοφία
Κυμιωνής, Γεώργιος
Φαρσάρη Μαρία
Reviewer Τσιλιμπάρης , Μιλτιάδης
Σιγανός, Χαράλαμπος
Abstract The cornea is a transparent tissue in front of the eye that refracts light and facilitates vision. A slight change in the geometry of the cornea remarkably affects the optical power. When the shape of the cornea changes due to an injury or a disease, then visual acuity is reduced and eyesight is lost in a large proportion, depending on the fault. The aim of this project was to construct a 3D model of cornea in high resolution, using biocompatible photosensitive materials. This was achieved with the method of Direct Laser Writing (DLW), a technology for the fabrication of 3D complex structures with high resolution. The interest in DLW has highly increased during the last years because of its various potential applications, such as in the field of mechanical, electronic, and optical microdevices, polymer based optical waveguides, optical data storage, biomedical applications, and other similar fields. A material for structuring by multiphoton polymerization must contain two basic components: a) a polymerizable material b) photoinitiator For this project, an inorganic-organic material was used. In the first part of the project we tried to make a 3D srtucture that represents the fibers of collagen of the cornea. In the second part of the study we tried to make more complex chess-like structures, with the same process (DLW). Firstly, the stucture was designed with the help of a CAD software and in a second step the structure was fabricated by Direct Laser Writing via the two-photon polymerization technique.
Language English
Subject Cornea
Direct laser writting
Απευθείας γραφή με λέιζερ
Κερατοειδής
Issue date 2016-03-24
Collection   School/Department--School of Medicine--Department of Medicine--Post-graduate theses
  Type of Work--Post-graduate theses
Permanent Link https://elocus.lib.uoc.gr//dlib/3/d/8/metadata-dlib-1456817686-794808-16601.tkl Bookmark and Share
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