Abstract |
Backround: Congenital infections can cause mortality and morbidity in all over the world, since there are numerous pathogens that can affect severely the fetus and impact the public health. Among them the most distinctive are hepatitis B, C, HIV, CMV, Toxoplasma gondii and rubella. The severity and the longterm of these diseases vary and can affect permanently the children and even cause death. In these cases the prevention through vaccination, health control of the pregnants and mostly through information about the ways of transmission of the diseases can occur to the reduction and hopefully to the extinction of the problem.
Methods: Demographic and serological data of all the pregnant women who delivered from January 2017to December 2018 in the public hospital of Agios Nikolaos were collected. Seroprevalence was estimated for HBV, HCV, HIV, Toxoplasma gondii, CMV and Rubella. Results were compared among ethnic groups and according to age.
Results: A total of 1128 medical records of routine prenatal screening were studied.The most prelevant age group of the participants was 30-39years.Their origin was Greek 74,6% for 2017 and 77,3% for 2018 and second more frequent “Balcania” 22,5% for 2017 18,7% for 2018. The mean seroprevalence was 0,3% for HBV, 22,4% and 21,7 for Toxoplasma gondii for 2017 and 2018 respectively, 67,4% and 66,5% for CMV for 2017 and 2018 respectively and 87,4% and 87,5% for Rubella for 2017 and 2018 respectively while neither HCV or HIV were detected. The seroprevalence of Greek women for HBV was 0,1% while from “Balkania” had a higher seroprevalence of 1,5%. Rubella immunity was documented in 87,4% of pregnant women.
Discussion: The present study concerns the effects of the congenital diseases (HBV, HCV, HIV, Toxoplasma gondii, CMV, Rubella) at Agios Nikolaos Public hospital. Important elements and facts raised which concern the inhabitants of the region of Lassithi. More specilically, the results indicate that the local population and the population of the island of Crete as a whole presents a low effectiveness in diseases such as HBV, HCV and HIV. Seroprevalence of Toxoplasma gondiiin Agios Nikolaos is low, putting women in high risk of getting affected during pregnancy.On the opposite side, seroprevalence of CMV is high giving protection to women during pregnancy. The prevention through control policies, vaccination, and routine health policies can reduction them. Concerning Rubella, the immunity is around 87,5% which can be improved in the future to the optimal target of >95%. Vaccination programs , and education of the obstrectic stuff may help recognizing vulnorable women even at the discharge of the hospital.
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