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Title Απομόνωση και χαρακτηρισμός ανάλογων του κοστικού οξέος σε εκχυλίσματα φύλλων του φυτού Dittrichia viscosa
Alternative Title Isolation and identification of costic acid analogs in plant extracts of Dittrichia viscose
Author Ραπούση, Μαρίνα
Thesis advisor Κατερινόπουλος, Χαράλαμπος
Abstract The Dittrichia viscosa plant contains plenty of secondary metabolites, such as flavonoids, terpenes, sesquiterpene lactones and sesquiterpene acids. The components of plant extracts, especially sesquiterpenoic acid, costic acid, are known for their acaricidal activity. In the context of further investigation of the plant components, attempts were made to isolate and identificate components of the extract with potential biological activity. Initially, the plant was harvested from the area of the University of Crete and extracted subsequently with Soxhlet and a mixture of 9: 1 solvents (PE / Acetone). The same process was carried out using a dried plant. The extracts were subjected to chromatographic separation.The components which were isolated are a mixture of α/β-costic acid, Ilicic acid, and 7-Omethylaromandedrin-3-acetate. The identification of the compounds was carried out using NMR (1D / 2D), GC-MS and LC-MS techniques.
Language Greek
Issue date 2018-07-18
Collection   School/Department--School of Sciences and Engineering--Department of Chemistry--Graduate theses
  Type of Work--Graduate theses
Permanent Link https://elocus.lib.uoc.gr//dlib/7/3/d/metadata-dlib-1531740397-962622-18278.tkl Bookmark and Share
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