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Identifier

000433816

Title

Development of graphene-based electrodes for bioelectronic devices

Alternative Title

Ανάπτυξη ηλεκτροδίων με βάση το γραφένιο για βιοηλεκτρονικές διατάξεις

Author

Πυλοστόμου, Αθανασία

Thesis advisor

Κιοσέογλου, Γεώργιος
Στρατάκης, Εμμανουήλ

Reviewer

Μητράκη, Άννα

Abstract

During the last decades, the field of bioelectronics is becoming increasingly important due to the demand for clinical detection of various diseases. Epilepsy is a common neurological disorder, affecting millions of people around the world. It is known that metabolic disturbances are often associated with the seizures of epilepsy. According to preliminary studies, amongst other biomarkers, glucose levels can be used for the prediction of incoming seizures, therefore, the creation of specific bioelectronic devices, such as biomolecular sensors, is of great importance. For neurological disorder detection, there is a tremendous need for hydrophilic, biocompatible and highly conductive electrodes in biosensors. Two-dimensional (2D) graphene-based nanomaterials (NMs) exhibit promising physical, optical and electrochemical properties for ultrasensitive bioelectronic devices. In this work, two dimensional (2D) reduced graphene oxide (rGO) based microelectrodes are developed for use in a biomolecular sensor. The graphene oxide (GO) films were mainly fabricated by spray gun technique. The topography and the composition of the GO films were studied by various microscopic and spectroscopic techniques, respectively. For the enhancement of the electronic properties, an ultrafast pulsed laser was used for the reduction of the GO material.

Language

English

Subject

Biosensors

Epilepsy

Graphene-based materials

Microelectrodes

Neurological disorders

Reduced graphene oxide

Βιοαισθητήρες

Επιληψία

Μικροηλεκτρόδια