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Identifier

000381640

Title

Χαρακτηρισμός της ανθεκτικότητας στο προνυμφοκτόνο Temephos στον κύριο φορέα των ιών της νόσου Chikungunya και του Δάγκειου Πυρετού, Aedes albopictus

Alternative Title

Characterization of larvicide Temephos resistance in the major Chikungunya and Dengue vector, Aedes albopictus

Author

Λυράκης, Εμμανουήλ

Thesis advisor

Βόντας, Ιωάννης

Reviewer

Λαδουκάκης, Εμμανουήλ
Πουλακάκης, Νικόλαος

Abstract

The mosquito Aedes albopictus is an adaptable organism, which primarily feeds on blood from mammals and other vertebrates and is considered to be one of the best invasive species. It expanded globally mainly during the last three decades, because of human activities. It is considered epidemiologically important and dangerous, because it can transmit numerous viruses and filarial nematodes and was responsible for the outbreak of Chikungunya fever in 2006 – 2007 worldwide. The management of mosquito populations contributes to the control of the diseases they transmit, with insecticides being the first line of defense. The contribution of insecticides in the control of Aedes populations was significant for several years, until resistance was developed. In this study, we tried to analyze and characterize the resistance of A. albopictus to larvicide Temephos, in a population which was collected from Greece, using the RNA – Seq technique. We conducted a differential expression analysis between two populations, which had the same genetic background and differences in insecticide levels. Many transcripts, which were found highly up – regulated, were related to detoxification genes. The most up – regulated transcript was related to carboxyl/cholinesterase CCEAE6A. These findings allow us to characterize the resistance of A. albopictus to larvicide Temephos as metabolic. The results of this analysis can be used for the early detection of resistance and the more effective control of A. albopictus. Its control is urgent, but can be better achieved through integrated management.

Language

Greek

Subject

Control

RΝΑ-SEQ technique

Ανθεκτικότητα

Καταπολέμηση

Τεχνική RNA-SEQ

Issue date

2013-11-15

Collection

School/Department--School of Sciences and Engineering--Department of Biology--Post-graduate theses