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Identifier

000433290

Title

Optical techniques to enhance the sensitivity of optical microscopy

Alternative Title

Οπτικές τεχνικές για την βελτίωση της ευαισθησίας της οπτικής μικροσκοπίας

Author

Βαρδάκης, Κωνσταντίνος Ν.

Thesis advisor

Παπάζογλου, Δημήτρης

Reviewer

Wolf, von Klitzing
Ρακιτζής, Πέτρος

Abstract

Much of the knowledge that we have from our world stems from images. Using optics and cameras, we can map how much light a sample absorbs or refracts and from that deduce the composition or physical structure of the sample. On the other hand, a limiting factor in optical microscopy is the sensitivity to minute refractive index changes. For example, when imaging biological cells, labeling has to be used since the minute changes in the real and imaginary part of the refractive index, induced by the cell’s inner workings, are practically invisible. Label-free imaging of the constituents of a living cell is still an open challenge In this master thesis we explored novel techniques that involve the use of optical cavities towards a goal to enhance the resolution of optical microscopy. Our study was focused on using theoretical tools and numerical simulations to analyze the behavior of optical cavities when used in combination with imaging systems. Based on our analysis we have designed such complex optical systems, optimized to be used for imaging applications.

Language

English

Subject

Cavity

Optics

Resonator

Κοιλότητα

Μικροσκοπία

Οπτική

Issue date

2020-11-20

Collection