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Identifier 000400140
Title Distributions of axial length and refractive error in patients with keratoconus
Alternative Title Κατανομές αξονικού μήκους και διαθλαστικού σφάλματος σε ασθενείς με κερατόκωνο
Author Παπαδογιάννης, Πέτρος
Thesis advisor Πλαϊνης, Σωτήρης
Παναγοπούλου, Σοφία
Κυμιωνής, Γιώργος
Reviewer Τσιλιμπάρης , Μ.
Δετοράκης, Ε.
Abstract Purpose: The research aims, through a cross-sectional study in patients with keratoconus, to check whether the balance between axial length-corneal power is disrupted, and show us if a keratoconic eye is relatively "large" or not , which could assess the development risk factor of keratoconus. Also , by evaluating the binocular differences in a group of children / young people, who usually have keratoconus in different stages in both eyes, it will be checked whether these certain differences are connected with any difference in axial length. Patients and Methods: This study involved 163 keratoconic patients and 175 emmetropes. Both eyes‘ data were recorded. These data were: a) the refraction of the eye which was taken by an automatic refractometer firstly, and by subjective refraction secondly b) the curvature of the cornea via corneal topography by Galilei c) the axial length and the anterior chamber depth of the eye using the IOL Master biometric system. The eyes of each subject were grouped based on keratoconus progress, in more progressed and less progressed keratoconus. The criteria were the astigmatism and the corneal radius. Statistical analysis was performed among the three groups: less progressed keratoconic eyes, more progressed keratoconic eyes and emmetropes. Results: The axial length found to have no significant difference between less and more progressed eyes, but the sphere and the cylinder differ significantly and are affected by the lower values in corneal radius(steeper cornea) because of the ectasia in more progressed eyes. The mean values for anterior chamber depth in less and more progressed keratoconus are 3.68mm and 3.74mm respectively, thus more progressed keratoconic eyes have longer anterior chamber depth. That difference though, does not affect the axial length. The keratoconic eyes found to be more myopic (longer) compared to the emmetropic group, and as expected, keratoconic corneas are much steeper than the emmetropic. Conclusion: The more progressed keratoconic eyes are more myopic but not longer (at a level that explains the difference of myopia) than the less progressed. Thus, the ectasia caused by keratoconus is the factor that affects the refractive profile in patients with keratoconus.
Language English
Issue date 2016-03-24
Collection   Faculty/Department--School of Medicine--Department of Medicine--Post-graduate theses
  Type of Work--Post-graduate theses
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