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Identifier 000389355
Title Συσχέτιση των επιπέδων των ανδρογόνων και των άλλων στεροειδών του φύλου και ψυχομετρικών παραμέτρων προσωπικότητας σε γυναίκες με φυσιολογικό κύκλο
Alternative Title Sex steroids and personality traits in the middle luteal phase of healthy normally menstruating young professional women
Author Αυγουστινάκη, Παυλίνα Δ.
Thesis advisor Παρίτσης, Νίκος
Reviewer Γραβάνης, Αχιλλέας
Καρκαβίτσας, Νίκος
Καστανάς, Ηλίας
Τόσκα, Ανδρονίκη
Παπαβασιλείου, Στάθης
Βενυχάκη, Μαρία
Abstract The aim of the present study was to determine the association, if any, between the circulating levels of gonadal and adrenal sex steroids in the midluteal phase (21st day of a normal menstrual cycle, MC) of young professional women and psychometric parameters as assessed by the official Greek translation of the Minnesota Multiphasic Personality Inventory (MMPI).

RESULTS: Our results are as follows:

a. The metabolic product of activated adrenal and gonadal androgens, 3alpha-diolG, was modestly but significantly associated with the social introversion scale (10-SI) (Spearman ρ=0.36, p<0.05), independently accounting for 13% of its variation across participants (R2=0.13, F(1.45)=6.58, p<0.01).

b. Total testosterone was significantly associated with the paranoia scale (6-Pa) (Spearman ρ=0.27, p<0.05). Multiple regression analyses indicated that 10% of the variability in paranoia scores could be independently explained by total testosterone levels (R2=0.10, F(1.57)=6.23, p<0.01). We were unable to find any association between the circulating androgens and scores on the masculinity-femininity scale (Mf). We were also unable to document any association between the weak adrenal androgens DHEA and DHEA-S and depression in contrast to several published reports.

c. Our data suggest a marginally significant association between progesterone and scores on the 7-Pt (obsessive / compulsive / psychasthenia) scale (Spearman ρ=0.27, p<0.05). However, only 7% of the 7-Pt variance was explained by progesterone (R2=0.071, F(1.50)=3.81, p<0.05).

CONCLUSIONS: We have found that total testosterone was associated with the paranoia score, the metabolic product of activated androgens, 3alpha-diolG, to social introversion and, finally, progesterone to obsessive-compulsive behavior.
Language Greek
Subject MMPI
Middle luteal
Personality
Phase
Sex steroids
Καταμήνιος κύκλος
Προσωπικότητα
Στεροειδή του φύλου
Issue date 2013-04-16
Collection   School/Department--School of Medicine--Department of Medicine--Doctoral theses
  Type of Work--Doctoral theses
Permanent Link https://elocus.lib.uoc.gr//dlib/9/c/d/metadata-dlib-1421664373-589480-9514.tkl Bookmark and Share
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