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Identifier 000382615
Title Επιδημιολογικά χαρακτηριστικά βρουκέλλωσης στην Ελλάδα και συσχέτιση με τη νόσο στα ζώα την περίοδο 2007-2012
Alternative Title Epidemiological Characteristics of Brucellosis in Greece and correlation with animal broucellosis
Author Φούσκης, Ιωάννης
Thesis advisor Ψαρουλάκη, Άννα
Reviewer Τζανάκης, Νικόλαος
Τσάτσαρης, Ανδρέας
Κεραμάρου, Μαρία
Abstract Brucellosis is the most common bacterial zoonosis worldwide according to the World Health Organization. The eradication of brucellosis in humans is consistent with the effective reduction of the disease in livestock . In Greece , the organized effort to fight the disease in sheep and goats began in 1975 with the subcutaneous (sc) vaccination of young sheep and goats. However after 38 years brucellosis is still endemic in Epirus, Western Macedonia , Thessaly, N. Peloponnese and Crete, where occasionally flares up. The purpose of this study is to record the incidence of brucellosis in humans and sheep and goat farms in the period 2007-2012 by county and region , to assess potential risk factors, to investigate the correlation between human outbreaks of brucellosis and disease in sheep and goats, and create the corresponding maps recording the disease nationwide The study spanned across Greek territory using the database of Hellenic Center for Disease Control & Prevention concerning the officially declared brucellosis cases and data from the Department of Zoonoses of Ministry of Rural Development and Food. The mean cumulative incidence for 2007-2012 was estimated at 1.43 / 100,000, while the percentage of positive farms estimated at 4.8 % and 0.87 % of tested and all holdings respectively. The risk is greater in men than women RR 2,17 (95% CI 1,89-2,49) and foreign RR 1,77 (95% CI 1,47-2,14). The age distribution of patients with brucellosis is different between men and women (x2 = 19.11 df = 4 p = 0,0007). In men the highest incidence value is at ages 25-44, while women in the last two cohorts 45-64,΄&γτ = 65. Male gender is associated (univariate) to engaging in dangerous occupation (x2 = 24,92, p ΄&λτ0,001) and recent contact with animals (x2 = 16,99, p ΄&λτ0,001). Similarly the female gender is associated to recent consumption of dairy products (x2 = 7,2, p = 0,007). In addition found that there is strong evidence that the incidence of brucellosis eradication zone is different from the vaccination area (p΄&λτ0,0001). Statistically significant correlation was also found between brucellosis and occurrence of the disease in animals , which Φούσκης Ιωάννης: Μεταπτυχιακή εργασία 2013 Π Μ Σ Δημόσια Υγεία & Διοίκηση Υπηρεσιών Υγείας 9 is more powerful in recent years (R2 = 0,85, p΄&λτ0,0001). The result of the statistical test showed ρ = -0,25714, (p΄&γτ 0,05) between vaccinated farms and cases of human brucellosis Brucellosis remains a major problem for public health and rural economy. The main route of infection in men seems to be the touch - through involvement with farming operations - while for women the consumption of dairy products. Control of the disease in the animal population so far is unsuccessful. Finally because of the association of the disease in animals and humans, an effective surveillance system and an admirable and interactive collaboration veterinary services and competent health professionals is essential to eradicate the disease in the country
Language Greek
Subject Brucellosis
Correlation
Hazard maps
Incidence
Risk factors
spatial analysis
Βρουκέλλωση
Επίπτωση
Παράγοντες κινδύνου
Συσχέτιση
Χάρτες επικινδυνότητας
Χωρική ανάλυση
Issue date 2014-01-22
Collection   School/Department--School of Medicine--Department of Medicine--Post-graduate theses
  Type of Work--Post-graduate theses
Permanent Link https://elocus.lib.uoc.gr//dlib/6/4/4/metadata-dlib-1393322001-511615-4192.tkl Bookmark and Share
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