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Identifier

000466098

Title

Μελέτη του ρόλου των πρωτεϊνών της οικογένειας Kinesin-7 στην καταπόνηση αλατότητας

Alternative Title

Study on the role of Kinesin-family proteins in salt stress

Author

Μαυρίδης, Κυριάκος Φ.

Thesis advisor

Μόσχου, Παναγιώτης

Abstract

Plants, being sessile organisms, must dynamically adjust to environmental stress through various processes, including protein stability regulation via autophagy and the ubiquitin-proteasome system (UPS). This study investigates the role of the kinesin-like protein KIN7.4 in Arabidopsis thaliana, particularly its involvement in salt stress. Our findings reveal that KIN7.4 knock-out mutants exhibit significant sensitivity to salt stress, unlike the closely related KIN7.2, highlighting a unique function for KIN7.4. We confirmed that KIN7.4 interacts with the Anaphase-Promoting Complex/Cyclosome (APC/C) inhibitor UVI4, and explored the possibility of KIN7.4 participating in endoreduplication. Furthermore, our data suggest that KIN7.4's interaction with UVI4 occurs along unidentified filamentous structures in the cytoplasm, possibly linking kinesin activity to cytoskeletal dynamics during stress adaptation. This study aims to enhance our understanding of the molecular pathways involving motor family proteins in plant stress responses, establishing a foundation for future research.

Language

English

Issue date

2024-07-26

Collection

School/Department--School of Sciences and Engineering--Department of Biology--Post-graduate theses

Type of Work--Post-graduate theses

Permanent Link

https://elocus.lib.uoc.gr//dlib/5/8/7/metadata-dlib-1721034448-235007-29721.tkl

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