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Identifier 000374774
Title Οικογεωγραφική μελέτη των ρικετσιών στην περιοχή της Σητείας
Alternative Title Study on ecology of rickettsiae in Sitia, Greece.
Author Γερμανάκης, Αντώνης
Thesis advisor Τσελέντης, Ιωάννης
Reviewer Γκίκας, Αχιλλέας
Αντωνίου, Μαρία
Σαμώνης, Γεώργιος
Παπαχατζή-Καλμαντή, Μαρία
Σκούλικα, Ευσταθία
Ψαρουλάκη, Άννα
Abstract The purpose of the this work was to study the Spotted Fever Group (SFG) Rickettsioses in Eastern Crete and especially in the area of Sitia. Methods: We recorded the clinical and epidemiological data from patients with rickettsiosis and we investigated the involving rickettsiae by molecular methods (PCR) and cell cultures from biological material of patients (blood, eschar), or by serology (IFA). We also investigated the chain of transmission by detection of rickettsiae in vectors and reservoirs. Results: The insidence of SFG rickettsioses was 34 cases / 100.000 persons. We described the clinical and epidemiological data from 34 patients. We documented the presence of Meditteranean Spotted Fever in Greece by isolation of 5 strains of R. conorii from 5 patients. We documented the presence of 2 emerging rickettsioses by detection of R. sibirica mongolotimonae and R. aeschlimannii from 2 patients. We also detected for first time a new species of rickettsia close related to R. africae in a patient, which has also been detected in ticks Rh. turanicus from Cyprus and Crete. The porposed name for this rickettsia is R. tselentii. We confirmed serologically the presence of rickettsioses due to R. felis and R. massiliae. We detected R. conorii in whole blood from dogs and in ticks Rh. sanguineus confirming the known ecology of R. conorii. Furthermore we detected for the first time R. conorii from sheep blood and from tick Rh. turanicus removed from a sheep. We suspect the presence of a second ecological cycle of R. conorii in this region which includes sheeps and ticks Rh. turanicus. We detected R. sibirica mongolotimonae in a tick Hyalomma anatolicum excavatum removed from a patient and also in the same tick species removed from sheeps. We suspect that ticks Hy. an. excavatum are vectors of R. sibirica mongolotimonae and that sheeps are involving in the ecology of this rickettsia. We also detected for first time R. aeschlimannii in a tick Rh. turanicus removed from a patient, implicating this tick species as vectors of R. aeschlimannii.
Language Greek
Subject Greece
Microbiology
Rickettsia
Spotted fever
Tick
Tick -borne disease
Κροτώνες
Μεσογειακός κηλιδώδης πυρετός
Πρόβατα
Ρικέτσια
Ρικετσιώσεις
Issue date 2011-07-15
Collection   School/Department--School of Medicine--Department of Medicine--Doctoral theses
  Type of Work--Doctoral theses
Permanent Link https://elocus.lib.uoc.gr//dlib/2/1/c/metadata-dlib-1339576486-984272-13823.tkl Bookmark and Share
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